Facebook has notoriously contrained customization, which is a good thing, however, there are a few ways to exploit some personalization in the way your profile page looks, without going the direction of Myspace.
A few weeks ago an artist posted one of the first adaptations of this customization below, with various other styles showing up.
This is my second take on it, using a photo I took on January 1.
Its pretty easy to do, you have to cut out images that match the dimensions of the thumbnails exactly (the left column image has to be the same width but as tall as you wish). I use the Gimp to do it, but photoshop works, and I here there is an actual facebook app to do it for you, now. The trick is tagging yourself in those thumbnails, in the order from right to left as they'll appear.